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Evidence is increasing that every addiction without exception is related to problems with the brain's reward center, specially the mesolimbic system. This the main problem regulates reward responses in establishing food and sex, along with nurturing infants and children. One of the most important neurotransmitters associated with reward responses, both once they malfunction and after they function properly, is dopamine. What makes opiates unique is that it, among other neurotransmitters modulates "the volume of dopamine released in responding to a stimulus"(Bostwick & Bucci, 2008).
Using two separate drugs to shed weight can be very effective there are combinations before the FDA now awaiting approval. When dealing with weight-loss and the people who go through it you should err assisting caution and allow FDA do its job and demand some research be done so your public recognizes the side effects and dangers of the medications before we bring them. Keep in mind that drug companies will be in business to generate income and that they would say anything to keep people on the medications.
Researchers found out that participants using this drug for a year, lost weight within 4 weeks and have kept the extra weight off through the 56 weeks with the study. Contrave is often a combination from the drugs naltrexone and bupropion, which generally seems to reflect a new trend of weight-loss drugs that are made up of multiple active ingredient, that might make them more efficient and safer.
Combo-pilling is the newest fad or better yet the newest into the future under scrutiny and therefore it is just more publicly known lately, comb-pilling for losing weight has been around since the eighties. The biggest reason that utilizing a combination of pills is now popular could be the fact that since right now there are no long term prescription weightloss pills that have been licensed by the FDA aside from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications and some of the combinations happen to be rejected or have yet to be approved by the FDA.
Seizures really are a side effect with Contrave and really should not be taken in those with seizure disorders. The drug may also raise hypertension and heartbeat, and must not be used in those with a history of heart attack or stroke in the earlier six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with all the drug.
The FDA also warned that Contrave can raise blood pressure and heartbeat and must not be used in patients with uncontrolled high blood pressure levels, along with by you aren't heart-related and cerebrovascular (circulation dysfunction impacting the brain) disease. Patients using a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes using a boxed warning to alert physicians and patients on the increased risk of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stopping smoking.
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